Esteban Burchard MD MPH

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Esteban Burchard MD MPH

Professor, Departments of Bioengineering & Therapeutic Sciences & Medicine, UCSF

Esteban González Burchard received his M.D. degree from Stanford University School of Medicine in 1995. He completed clinical training in Internal Medicine at Harvard’s Brigham and Women’s Hospital and Pulmonary/Critical Care Medicine training at UCSF. Dr. Burchard also completed clinical research training at the Harvard School of Public Health. He joined the UCSF faculty in 2001. In 2006 he received his Master’s in Public Health from UC Berkeley. Dr. Burchard’s major academic interest centers on identifying genetic risk factors for asthma in ethnically diverse populations. In addition, Dr. Burchard co-directs the UCSF/SFGH DNA Banking Facility located at San Francisco General Hospital. The UCSF DNA Bank is a central core facility that is available to all UCSF investigators involved in translational genetic research.

It is well established that among U.S. residents of similar socioeconomic status, there is greater asthma morbidity and mortality among African Americans and Latino Americans than among Caucasians Americans. In addition, the reported rates of asthma morbidity and mortality differ strikingly among specific Latino American ethnic groups. Specifically, reported rates of asthma morbidity and mortality are higher among Puerto Rican Americans than among Mexican Americans. This is in stark contrast to the near geographic uniformity of asthma morbidity and mortality rates among African American and Caucasians. Although there are many potential explanations for this observation, including environmental and socioeconomic factors, one potential explanation is that the genetic predisposition to asthma or to greater asthma severity differs among subgroups within the Latino population. These genetic subgroups may have genetic variants (alleles) of asthma candidate genes, which may explain the variation in asthma prevalence, asthma severity and bronchodilator drug responsiveness in Latino ethnic groups.

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