Read more about Dr. Kadoch’s presentation at the conference.
Assistant Professor, Pediatric Oncology, Dana-Farber Cancer Institute and Harvard Medical School. Associate Member, Center for the Science of Therapeutics Broad Institute. Recently named as one of 2013 Forbes '30 under 30' list Cigall Kadoch, as a post-doctoral scholar at Stanford Medical School, helped identify a group of proteins that appear to play a significant role in the suppression of many types of cancer.
Working alongside renowned developmental biologist Gerald Crabtree, Kadoch used a series of biochemical experiments in combination with data-mining to identify the protein set, known as BAF, which regulates chromatin structure in cells. Kadoch and her colleagues were able to link mutations in molecular subunits of the BAF complex to more than one-fifth of human cancers.As an associate member of the Broad’s Cancer Program, and an assistant professor of pediatric oncology at Dana-Farber Cancer Institute and Harvard Medical School, Kadoch is applying her knowledge of chromatin regulation and biochemistry to develop new therapies for cancers with BAF mutations.